The Antibacterial Activities of Thiazoles, Substituted Thiazoles and Their Metal Complexes- A Review.

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منابع مشابه

Syntheses, Antibacterial and Antifungal Activities of Substituted-Thiazolo-1,3,4-Thiadiazoles, 1,3,4-Oxadiazoles and 1,2,4-Thiazoles

Starting from readily available 2-substituted-4-methylthiazole-5-carboxylic acid hydrazide (1), The title compounds were prepared. The reaction of compound 1 (R=CH3) with formic acid yielded 1-(formyl)-2-(2,4-dimethylthiazole-5-carboxyl) hydrazine (2). Refluxing the latter with phosphorous pentasulfide in xylene afforded compound 3, the reaction of compound 2 with phosphorous pen...

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Diverse biological activities of Thiazoles: A Retrospect

Many compounds bearing five membered heterocyclic rings in their structure have an extensive spectrum of biological activities. The search for new biologically active thiazole analogues continues to be an area of intensive investigation in medicinal chemistry. The present review describes ongoing research in search for new thiazole compounds that can prove useful for the design of future target...

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syntheses, antibacterial and antifungal activities of substituted-thiazolo-1,3,4-thiadiazoles, 1,3,4-oxadiazoles and 1,2,4-thiazoles

starting from readily available 2-substituted-4-methylthiazole-5-carboxylic acid hydrazide (1), the title compounds were prepared. the reaction of compound 1 (r=ch3) with formic acid yielded 1-(formyl)-2-(2,4-dimethylthiazole-5-carboxyl) hydrazine (2). refluxing the latter with phosphorous pentasulfide in xylene afforded compound 3, the reaction of compound 2 with phosphorous pentoxide afforded...

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Studies of Transition Metal Complexes and Their Antibacterial Activities

Tetraaza Macrocyclic complexes of transition metals of Ni (II), Cu(II), Cr(III), Fe(III), Mn(II) were synthesized in methanolic media by template method. The complexes were characterized by elemental analysis, UVVis, Infrared spectroscopy. In vitro antibacterial activity of macrocyclic complexes against five bacteria i.e. Streptococcus mutans, Escherichia coli, Staphylococcus aureus, Streptococ...

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Antiprotozoal thiazoles. 2. 2-(5-Nitro-2-furyl-, thiazolyl-, and 1-methylimidazolyl-)thiazoles.

Ten 2-substituted 4-thiazolecarboxaldehyde hydrazones bearing 5-nitro-2-furyl, 5-nitro-2-thiazolyl, and 1-methyl-5-nitro-2-imidazolyl functions have been prepared and screened for activity against Trypanosoma cruzi infections in mice. The results permitted the ranking of these substituents in decreasing order of activity: 1-methyl-5-nitro-2-imidazolyl greater than 5-nitro-2-furyl greater than 5...

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ژورنال

عنوان ژورنال: Journal of Current Pharma Research

سال: 2012

ISSN: 2230-7834,2230-7842

DOI: 10.33786/jcpr.2012.v03i01.009